Published online 2009 May 24. doi: 10.1053/j.gastro.2009.05.044
Duncan, Andrew W. et al.
Stem cells for Liver Disease
The liver is a very important
organ for us humans. Its main job is to be a filter, it’s like our very own
treatment plant. It’s in charge of filtering the blood after it passes through
the digestive system, detoxifies chemicals and metabolizes drugs and alcohol.
As important as it is, there’s also a wide variety of diseases and conditions
that affect liver function. They may be inherited or they may be caused by
factors such as viruses or alcohol abuse which causes scarring, leading
potentially to cirrhosis.
Evidence suggests that fat
derived stem cells will develop hepatocyte like functions in presence of
hepatocyte cell populations and while the exact interactions are unknown,
results suggest there is an increase in liver regeneration. The use of basic
fibroblast growth factor enhances the therapeutic effect of the treatment.