Rheumatoid arthritis (RA), is a chronic system wide inflammatory disorder that may affect many tissues and organs. RA is considered a systemic autoimmune disease where essentially, antibodies in the body attack the patient's own healthy cells .Although the cause of RA is unknown, autoimmunity plays a pivotal role in both its chronic status and progression. RA primarily attacks the joints. The Disease process often leads to the decay of articular cartilage and ankylosis (abnormal immobility and fusion of bones) of the joints. Rheumatoid Arthritis can also produce diffuse inflammation in the lungs, pericardium, pleura, and sclera, and also nodular lesions, most common in subcutaneous tissue.